01 - Pat chicken breasts dry with paper towels and season both sides generously with 1 teaspoon salt and 1/2 teaspoon black pepper.
02 - In a large bowl, whisk together buttermilk, hot sauce, chopped jalapeños, and minced garlic until well combined.
03 - Submerge seasoned chicken breasts in the marinade, ensuring complete coverage. Cover and refrigerate for at least 1 hour, or up to overnight for maximum flavor penetration.
04 - In a shallow dish, combine flour, cornmeal, smoked paprika, cayenne pepper, garlic powder, onion powder, 1/2 teaspoon salt, and 1/2 teaspoon black pepper. Mix thoroughly to distribute spices evenly.
05 - Remove chicken from marinade, allowing excess liquid to drip off. Press each piece firmly into the breading mixture, coating completely on all sides. Transfer to a wire rack.
06 - Pour vegetable oil to a depth of 2 inches in a deep skillet or Dutch oven. Heat to 350°F, maintaining temperature throughout frying.
07 - Working in batches to avoid overcrowding, fry chicken breasts for 6 to 8 minutes per side until golden brown and crispy. Verify internal temperature reaches 165°F for safe consumption.
08 - Transfer cooked chicken to a clean wire rack or paper towels to drain excess oil. Let rest for 5 minutes before serving to retain juices.